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Chengxun Liu    
   

 

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Bio

CHENGXUN LIU, IMEC
TEAM LEADER MICROFLUIDICS, LIFE SCIENCE AND IMAGING


Chengxun Liu, Ph.D., microfluidics team leader in the Life Science & Imaging department, imec. Chengxun received his bachelor degree in mechanical engineering and master degree in biology from Tsinghua University, China. He then moved to Belgium where he obtained the doctoral degree in electrical engineering at K.U.Leuven and imec. Since 2003 Chengxun conducted research in lab-on-chip technologies. The topics include microfluidic actuation, high speed cell sorting as well as cell & biomolecule isolation by electrical and magnetic methods. Since 2006 one of his major research interest is the isolation of analysis of circulating tumor cells (CTC) using micro technologies such as microfluidic immunomagnetic isolation, micro filtration, electrical impedance spectroscopy and vapor bubble cell sorting. For this topic, he has been leading and conducting several projects such as the EU MASCOT and MIRACLE project. Chengxun is currently responsible for the technology research and development of the microfluidics team at imec.

 

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Presentation abstract

SAMPLE PREPARATION: PICK AND DELIVER THE RIGHT TARGET FOR ANALYSIS

Continuous innovations in transducers and nanoelectronics start to allow rare cell or biomolecule analysis in liquid biopsy. Nowadays, single cell sequencing and single molecule detection become possible. However, there is still a significant gap between the liquid biopsy sample intake and the end-point analysis (e.g. gene sequencing), because the sample is often too complex to be directly analyzed. Therefore, liquid biopsy calls for an accurate, efficient and automated sample preparation method which can isolate the target cells or molecules for downstream analyses. This is of utmost importance in the clinical environment. The fast growing microfluidics technology is a most promising candidate for liquid biopsy sample preparation, because of the power of handling trace amount of target cells or molecules in a complex background. In this talk we will take a glance at the state-of-the-art microfluidics technology and how it addresses sample preparation challenges in liquid biopsy.

 

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