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Tim Denison    
   

 

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Bio

TIM DENISON, MEDTRONIC
VP OF RESEARCH & CORE TECHNOLOGY, TECHNICAL FELLOW

Tim is the Vice President of Research and Core Technology, Implantable Systems, for the Restorative Therapies group of Medtronic PLC.  He was named a technical fellow in 2010, received Medtronic's highest technical and scientific award, membership in the Bakken Society in 2012 and was honored with the Wallin Leadership Award in 2014. Tim was named to the College of Fellows for the American Institute of Medical and Biological Engineering in 2015.

Tim Denison received his M.S. and Ph.D. in Electrical Engineering from the Massachusetts Institute of Technology, and his A.B. in Physics from the University of Chicago. He is currently completing an MBA at the University of Chicago.

Tim’s extracurricular pursuits include serving as an adjunct professor at Brown University, volunteering as an assistant editor for the IEEE Transactions on Biomedical Circuits and Systems/Biomedical Engineering, and on the editorial board of the Journal of Neural Engineering.

 

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Presentation abstract

FROM BRAIN OBSERVATORIES TO SCIENTIFIC PAYLOADS: STRATEGIES FOR CATALYZING TRANSLATIONAL NEUROSCIENCE TO ADDRESS DISEASE

Neurological disease has a significant economic and societal impact. While promising in-roads for treatment have been made for some conditions, many disorders continue to be plagued by limited understanding of the underlying pathophysiology and  the therapeutic mechanisms of existing and potential treatments. To address this issue, teams are creating investigational research tools, with advanced bioelectronic designs, that can be chronically implanted to study the nervous system. These tools permit the active probing of malfunctioning neural circuits with novel instrumentation, enabled by a system architecture that leverages an existing neurostimulator’s potential “scientific payload” to provide a chronic conduit to the nervous system. Deployed with clinician-researchers, these instrumentation toolkits bootstrap off existing clinical care pathways to facilitate exploration of therapeutic concepts. This strategy enables a new approach to translational research, merging engineering design methods with basic neuroscience to help catalyze the next generation of neurological therapies. This talk will provide a technical perspective on the state-of-the-art for this work, some promising areas for exploration, and the significant challenges that remain.

 

 

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